Title of article :
Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids as potential DNA-binding agents
Author/Authors :
Ahmed Kamal، نويسنده , , O Srinivas، نويسنده , , P Ramulu، نويسنده , , G Ramesh، نويسنده , , P.Praveen Kumar، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
Pyrrolobenzodiazepine hybrids linked to acridone/acridine ring systems at C8-position have been designed and prepared that exhibit significant DNA-binding affinity, and a representative compound shows promising in vitro anticancer activity.
Keywords :
ahmedkamal@ins.iictnet.com , Pyrrolobenzodiazepine , acridone , Acridine , DNA-binding affinity , In vitro anticancer activity.* Corresponding author. Tel.: +91-40-27193157 , fax: +91-40-27193189 , e-mail addresses: ahmedkamal@iict.res.in
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
