Title of article
Structure–activity relationships of methylene or terminal side chain modified retinoids on the differentiation and cell death signaling in NB4 promyelocytic leukemia cells
Author/Authors
Diana Ivanova، نويسنده , , Aurélie Rossin، نويسنده , , Hinrich Gronemeyer، نويسنده , , Alain Valla، نويسنده , , Dominique Cartier، نويسنده , , Régis Le Guillou، نويسنده , , Roger Labia، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
4257
To page
4261
Abstract
New structure–activity relationships of a series of methylene or side chain modified retinoids on NB4 acute promyelocytic leukemia cells are investigated. The differentiation- and apoptosis-inducing potential of these compounds is analyzed on the basis of their selective retinoic acid receptor binding profile.
Keywords
leukemia , Apoptosis. , differentiation , Retinoids , RAR selectivity , Rexinoids
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794774
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