Title of article
Synthesis, structural properties and insulin-enhancing potential of bis(quercetinato)oxovanadium(IV) conjugate
Author/Authors
Ruchi Shukla، نويسنده , , Vivek Barve، نويسنده , , Subhash Padhye، نويسنده , , Ramesh Bhonde، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
5
From page
4961
To page
4965
Abstract
An oxovanadium complex of quercetin (2), exhibits highly potent insulin-enhancing activity in streptozotocin-induced diabetic mice. It also mimics mitogenic potential of insulin as evaluated by [H3]thymidine uptake assay making an effective, orally active insulin-enhancing agent for the treatment of both type 1 and type 2 diabetes without any noticeable toxic effects.
Keywords
Quercetin , Vanadium complex , fax: +91-20-2569-2259 , e-mail: rrbhonde@nccs.res.in , Insulin mimic , Diabetes.* Corresponding author. Tel.: +91-20-2569-0922
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794908
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