Title of article
5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP
Author/Authors
Richard Sulsky، نويسنده , , Jeffrey A. Robl، نويسنده , , Scott A. Biller، نويسنده , , Thomas W. Harrity، نويسنده , , John Wetterau، نويسنده , , Fergal Connolly، نويسنده , , Kern Jolibois، نويسنده , , Lori Kunselman، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
4
From page
5067
To page
5070
Abstract
5-Carboxamido-1,3,2-dioxaphosphorinanes have been identified as potent inhibitors of microsomal triglyceride-transfer protein. The 1,3,2-dioxaphosphorine functionality acted as a neutral and stable replacement for piperidine and piperidine N-oxide.
Keywords
MTP inhibitors , e-mail: sulskyr@bms.com , fax: +1 609 8186810 , Cyclophosphonates.* Corresponding author. Tel.: +1 609 8184730
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2004
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
794928
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