Title of article :
4-Acylamino-and 4-ureidobenzamides as melanin-concentrating hormone (MCH) receptor 1 antagonists
Author/Authors :
Jean-Marie Receveur، نويسنده , , Emelie Bjurling، نويسنده , , Trond Ulven، نويسنده , , Paul Brian Little، نويسنده , , Pia K. N?rregaard، نويسنده , , Thomas H?gberg، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
Synthesis, in vitro biological evaluation and structure–activity relationships of 4-acylamino-and 4-ureidobenzamides as novel hMCH1R-antagonists are disclosed. The nature of the amine side chains could be varied considerably in contrast to the central benzamide scaffold and aromatic substituents.
Keywords :
Melanin-concentrating hormone receptor 1 , MCH1 , MCH1receptor , MCH1 receptor antagonists , Structure–activity relationships , Benzamides.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
