Title of article :
Synthesis and in vitro study of novel Mannich bases as antibacterial agents
Author/Authors :
Sheela Joshi، نويسنده , , Navita Khosla، نويسنده , , Deepak Khare، نويسنده , , Rakesh Sharda، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A series of novel Mannich bases derived from 5-chloro-2-methoxybenzamide and sulfonamides/amines have been synthesised and the antibacterial activities were evaluated against various Gram positive and Gram negative strains of bacteria. Some of the synthesized compounds showed superior in vitro activities as compared to their parent sulfonamides.
Keywords :
sulfonamides , 5-Chloro-2-methoxybenzamide , Antibacterial activity , statistical analysis , LD50 test , Mannich bases
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
