Title of article
Synthesis and in vitro study of novel Mannich bases as antibacterial agents
Author/Authors
Sheela Joshi، نويسنده , , Navita Khosla، نويسنده , , Deepak Khare، نويسنده , , Rakesh Sharda، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
6
From page
221
To page
226
Abstract
A series of novel Mannich bases derived from 5-chloro-2-methoxybenzamide and sulfonamides/amines have been synthesised and the antibacterial activities were evaluated against various Gram positive and Gram negative strains of bacteria. Some of the synthesized compounds showed superior in vitro activities as compared to their parent sulfonamides.
Keywords
sulfonamides , 5-Chloro-2-methoxybenzamide , Antibacterial activity , statistical analysis , LD50 test , Mannich bases
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795182
Link To Document