• Title of article

    Enantiomerical excess determination, purification and biological evaluation of (3S) and (3R) α,β-butenolide analogues of isobenzofuranone

  • Author/Authors

    Emmanuelle Lipka، نويسنده , , Marie-Pierre Vaccher، نويسنده , , Claude Vaccher، نويسنده , , Christophe Len، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    4
  • From page
    501
  • To page
    504
  • Abstract
    The asymmetric synthesis of isobenzofurane analogues, new potential antiviral agents, is reported. High performance liquid chromatography (HPLC) was the technique chosen to separate the enantiomers. We describe this chiral separation and then determine the enantiomerical excess. The biological results of each tested enantiomer are given.
  • Keywords
    HIV , nucleoside , Chiral HPLC
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2005
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    795231

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=795231