Title of article :
New conformationally locked bicyclic N,O-nucleoside analogues of antiviral drugs
Author/Authors :
Antonio Procopio، نويسنده , , Stefano Alcaro، نويسنده , , Antonio De Nino، نويسنده , , Loredana Maiuolo، نويسنده , , Francesco Ortuso، نويسنده , , Giovanni Sindona، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
In order to obtain rigidity within the sugar moiety of nucleosides, the bicyclic pyrimidine derivatives of N,O-isoxazolidines were designed and synthesized by using 1,3-dipolar cycloaddition of Δ1-pyrrolidine-1-oxide and the appropriate vinyl-nucleobases.
Keywords :
N , Vinylpyrimidine nucleobases , O-Isoxazolidines , Nucleoside analogues
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
