Title of article
Dipyridyl amides: potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists
Author/Authors
Céline Bonnefous، نويسنده , , Jean-Michel Vernier، نويسنده , , John H. Hutchinson، نويسنده , , Janice Chung، نويسنده , , Grace Reyes-Manalo، نويسنده , , Theodore Kamenecka، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
1197
To page
1200
Abstract
The mGlu5 receptor has been implicated in a number of CNS disorders. Herein, we report on the discovery, synthesis, and biological evaluation of dipyridyl amides as small molecules mGluR5 antagonists.
Keywords
mGluR5 , Amides , CNS disorders
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795364
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