Title of article
QSAR studies on 1,2-dithiole-3-thiones: modeling of lipophilicity, quinone reductase specific activity, and production of growth hormone
Author/Authors
Padmakar Khadikar، نويسنده , , Mona Jaiswal، نويسنده , , Madhu Gupta، نويسنده , , Dheeraj Mandloi، نويسنده , , Raj Singh Sisodia، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
7
From page
1249
To page
1255
Abstract
Studies on modeling of lipophilicity (log P) quinone reductase specific activity (logCDQR) and production of growth hormone (logCDGH) of 1,2-dithiole-3-thiones have been carried out using distance-based topological indices. The regression analysis of the data has shown that the set of compounds exhibit ‘familial’ relationships in that excellent results are obtained by dividing the data set into two or more classes (families).
Keywords
Lipophilicity , Quinone reluctance specific activity , Productive growth hormones , topological indices , Dithioles , Thiones
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795375
Link To Document