Title of article
Design, synthesis and biological evaluation of novel bicyclic β-lactams as potential antimalarials
Author/Authors
Manisha Nivsarkar، نويسنده , , D. Thavaselvam، نويسنده , , C. S. Prasanna Kumar، نويسنده , , Mamta Sharma، نويسنده , , M.P. Kaushik، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
3
From page
1371
To page
1373
Abstract
A series of bicyclic N-substituted and unsubstituted β-lactams were synthesized and evaluated as targeted potential antimalarials. The compounds MNR4 and MNR5 were found to have highest potency against Plasmodium falciparum in vitro.
Keywords
Plasmodium falciparum , bicyclic , Antimalarial , ?-lactam
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795398
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