Title of article
(E)-Phenyl- and -heteroaryl-substituted O-benzoyl-(or acyl)oximes as lipoprotein-associated phospholipase A2 inhibitors
Author/Authors
Tae-Sook Jeong، نويسنده , , Mi-Jeong Kim، نويسنده , , Hana Yu، نويسنده , , Kyung Soon Kim، نويسنده , , Joong-Kwon Choi، نويسنده , , Sung-Soo Kim، نويسنده , , Woo Song Lee، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
3
From page
1525
To page
1527
Abstract
A series of (E)-phenyl- and -heteroaryl-substituted O-benzoyl- (or acyl)oximes 3a–n were synthesized for evaluating their human lipoprotein-associated phospholiphase A2 (Lp-PLA2) inhibitory activities. The less lipophilic derivatives 3a–c showed the most potent in vitro inhibitory activity on human Lp-PLA2.
Keywords
Lp-PLA2 inhibitor
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795430
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