Title of article
Design, synthesis and activity of novel derivatives of Oxybutynin and Tolterodine
Author/Authors
Kirandeep Kaur، نويسنده , , Shelly Aeron، نويسنده , , Miriyala Bruhaspathy، نويسنده , , Shankar J. Shetty، نويسنده , , Suman Gupta، نويسنده , , Laxminarayan H. Hegde، نويسنده , , Arun D.V. Silamkoti، نويسنده , , ANITA MEHTA، نويسنده , , Anita Chugh، نويسنده , , Jang B. Gupta، نويسنده , , P.K.S. Sarma، نويسنده , , Naresh Kumar، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
2093
To page
2096
Abstract
Novel derivatives of Tolterodine (1) and Oxybutynin (2) have been designed using conformationally restricted azabicyclics as replacement for open-chain amines. The synthesis and structure–activity relationships are presented.
Keywords
oxybutynin , Tolterodine , Azabicyclohexane , elective muscarinic antagonists
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795538
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