Title of article
Identification of chemokine receptor CCR4 antagonist
Author/Authors
Ashok V. Purandare، نويسنده , , Aiming Gao، نويسنده , , Honghe Wan، نويسنده , , John Somerville، نويسنده , , Christine Burke، نويسنده , , Carrie Seachord، نويسنده , , Wayne Vaccaro، نويسنده , , John Wityak، نويسنده , , Michael A. Poss، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
2669
To page
2672
Abstract
The present study reports the identification and hits to leads optimization of chemokine receptor CCR4 antagonists. Compound 12 is a high affinity, non-cytotoxic antagonist of CCR4 that blocks the functional activity mediated by the receptor.
Keywords
Chemokine receptor CCR4 antagonist
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795649
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