Title of article
New inhibitors of rabbit muscle triose-phosphate isomerase
Author/Authors
M. Fonvielle، نويسنده , , Roberto S. Mariano، نويسنده , , M. Therisod، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
2906
To page
2909
Abstract
We describe the synthesis and evaluation of three new competitive inhibitors of triose-phosphate isomerase. One of them (phosphoglycoloamidoxime: Ki = 4.5 μM) is among the best reversible inhibitors so far reported for this enzyme.
Keywords
Phosphonate inhibitors , Phosphoglycoloamidoxyme , Phosphoglycolohydrazide , Class II fructose-bisphosphate aldolase , Enzyme inhibitor , Triose-phosphate isomerase
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795696
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