Title of article :
New inhibitors of rabbit muscle triose-phosphate isomerase
Author/Authors :
M. Fonvielle، نويسنده , , Roberto S. Mariano، نويسنده , , M. Therisod، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
We describe the synthesis and evaluation of three new competitive inhibitors of triose-phosphate isomerase. One of them (phosphoglycoloamidoxime: Ki = 4.5 μM) is among the best reversible inhibitors so far reported for this enzyme.
Keywords :
Phosphonate inhibitors , Phosphoglycoloamidoxyme , Phosphoglycolohydrazide , Class II fructose-bisphosphate aldolase , Enzyme inhibitor , Triose-phosphate isomerase
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
