Title of article
Synthesis and biological evaluation of novel 1,4-naphthoquinone derivatives as antibacterial and antiviral agents
Author/Authors
Vishnu K. Tandon، نويسنده , , Dharmendra B. Yadav، نويسنده , , Ravindra V. Singh، نويسنده , , Meenu Vaish، نويسنده , , Ashok K. Chaturvedi، نويسنده , , Praveen K. Shukla، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
3463
To page
3466
Abstract
A series of 1,4-naphthoquinone derivatives were synthesized and evaluated for antibacterial and antiviral activities. The structure–activity relationships of these compounds were also studied. The results suggest that compounds 9–22 showed in vitro marked antibacterial activity. Compounds 4c and 7a showed inhibitory effect against RNA dependent RNA polymerase induced poliovirus type 2 infected HeLa cells.
Keywords
1 , MIC , antiviral , Antibacterial , 4-Naphthoquinone derivative
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795812
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