Author/Authors :
Gianna Allegrone، نويسنده , , Elisabetta Brenna، نويسنده , , Giovanni Fronza، نويسنده , , Claudio Fuganti، نويسنده , , Tommaso Giovenzana، نويسنده , , Luciana Malpezzi، نويسنده , , Enrico Barlocchi، نويسنده , , Cesare Pellegatta، نويسنده ,
Abstract :
The structure of an impurity contained in samples of all trans-retinoic acid was established by means of NMR and MS spectra, and confirmed by X-ray diffraction analysis. The chemical structure of the impurity 2 was found to be strictly correlated to the synthetic procedure employed for the preparation of the retinoic acid samples. Single crystal analysis allowed us to characterise the molecular conformation and the crystal structure of 2.
