Title of article
Impurity analysis of retinoic acid samples
Author/Authors
Gianna Allegrone، نويسنده , , Elisabetta Brenna، نويسنده , , Giovanni Fronza، نويسنده , , Claudio Fuganti، نويسنده , , Tommaso Giovenzana، نويسنده , , Luciana Malpezzi، نويسنده , , Enrico Barlocchi، نويسنده , , Cesare Pellegatta، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
3528
To page
3531
Abstract
The structure of an impurity contained in samples of all trans-retinoic acid was established by means of NMR and MS spectra, and confirmed by X-ray diffraction analysis. The chemical structure of the impurity 2 was found to be strictly correlated to the synthetic procedure employed for the preparation of the retinoic acid samples. Single crystal analysis allowed us to characterise the molecular conformation and the crystal structure of 2.
Keywords
Retinoic acid , Impurity , Allylic oxidation
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795825
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