• Title of article

    Synthesis and biological evaluation of novel angularly fused polycyclic coumarins

  • Author/Authors

    Imtyaz A. Khan، نويسنده , , Manjunath Ghate and Manohar V. Kulkarni، نويسنده , , M. Gopal، نويسنده , , M.S. Shahabuddin، نويسنده , , Chung-Ming Sun، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    4
  • From page
    3584
  • To page
    3587
  • Abstract
    In a three-step sequence, an array of angularly fused polycyclic heterocycles with coumarin, benzofuran and pyridine rings were synthesized from 4-bromomethylcoumarins and salicylonitrile. All the final compounds were fully characterized and screened for anti-microbial, anti-inflammatory and analgesic activities. Several compounds exhibited promising inflammation inhibiting and anti-microbial properties.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2005
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    795838