Title of article :
Neuroprotective effects of naturally occurring biflavonoids
Author/Authors :
Sam Sik Kang، نويسنده , , Ji Yeon Lee، نويسنده , , Yoo Keum Choi، نويسنده , , Sun Sook Song، نويسنده , , Ju Sun Kim، نويسنده , , Su Jin Jeon، نويسنده , , Yong Nam Han، نويسنده , , Kun Ho Son، نويسنده , , Byung Hee Han، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
We examined neuroprotective effects of naturally occurring biflavonoids on oxidative stress-induced and amyloid β peptide-induced cell death in neuronal cells. Among the nine biflavonoids tested, amentoflavone, ginkgetin, and isoginkgetin exhibited strong neuroprotection against cytotoxic insults induced by oxidative stress and amyloid β, suggesting their therapeutic potential against neurodegenerative diseases, including ischemic stroke and Alzheimer’s disease.
Keywords :
Flavonoids , Amentoflavone , neuroprotection , ischemic stroke , Alzheimer’s disease , Biflavonoids
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
