Title of article :
Design, synthesis, and evaluation of novelly substituted benzimidazole compounds as angiotensin II receptor antagonists
Author/Authors :
Alka Bali، نويسنده , , Yogita Bansal، نويسنده , , M. Sugumaran، نويسنده , , Jatinder Singh Saggu، نويسنده , , P. Balakumar، نويسنده , , Gurpreet Kaur، نويسنده , , Gulshan Bansal، نويسنده , , Ajay Sharma، نويسنده , , Manjeet Singh، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
5-Nitrobenzimidazole derivatives with varying substituents at 2-position have been designed, synthesized, and evaluated for angiotensin II antagonistic activity. A drug–receptor interaction model has been proposed.
Keywords :
5-Substituted benzimidazole , angiotensin II , Antagonists , Candesartan , losartan
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
