Title of article
Solid-phase synthesis and anti-infective activity of a combinatorial library based on the natural product anisomycin
Author/Authors
Shuhao Shi، نويسنده , , Shirong Zhu، نويسنده , , Samuel W. Gerritz، نويسنده , , Kim Esposito، نويسنده , , Ramesh Padmanabha، نويسنده , , Wenying Li، نويسنده , , John J. Herbst، نويسنده , , Henry Wong، نويسنده , , Yue-Zhong Shu، نويسنده , , Kin S. Lam، نويسنده , , Michael J. Sofia، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
4151
To page
4154
Abstract
The solid-phase synthesis of a library based on the natural product anisomycin is described. The resulting library was tested against a panel of bacterial and fungal targets, and active compounds were identified in a Staphylococcus aureus whole-cell assay and an efflux-deficient fungal whole-cell assay.
Keywords
Candida albicans , fungal , antibiotics , Anisomycin library , Staphylococcus aureus , solid-phase synthesis
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795950
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