Title of article
Dipyridyl amines: Potent metabotropic glutamate subtype 5 receptor antagonists
Author/Authors
Theodore M. Kamenecka، نويسنده , , Céline Bonnefous، نويسنده , , Steven Govek، نويسنده , , Jean-Michel Vernier، نويسنده , , John Hutchinson، نويسنده , , Janice Chung، نويسنده , , Grace Reyes-Manalo، نويسنده , , Jeffery J. Anderson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
4
From page
4350
To page
4353
Abstract
Modulation of the metabotropic glutamate subtype 5 (mGlu5) receptor may be useful in the treatment of a variety of central nervous system disorders. Herein, we report on the discovery, synthesis, and biological evaluation of dipyridyl amines as small molecule mGlu5 antagonists.
Keywords
mGlu5 , Metabotropic
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2005
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
795991
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