• Title of article

    Inhibition of Src kinase activity by 7-[(2,4-dichloro-5-methoxyphenyl)amino]-2-heteroaryl-thieno[3,2-b]pyridine-6-carbonitriles

  • Author/Authors

    Diane H. Boschelli، نويسنده , , Biqi Wu، نويسنده , , Ana Carolina Barrios Sosa، نويسنده , , Joan J. Chen، نويسنده , , Jennifer M. Golas، نويسنده , , Frank Boschelli، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2005
  • Pages
    4
  • From page
    4681
  • To page
    4684
  • Abstract
    7-[(2,4-Dichloro-5-methoxyphenyl)amino]thieno[3,2-b]pyridine-6-carbonitriles with various heteroaryl groups at C-2 are inhibitors of Src kinase activity. Of these new analogs, compounds substituted at C-2 by a 3,5-furan or a 2,5-pyridine had the best activity in the Src enzyme and cell assays.
  • Keywords
    2-b]pyridine-6-carbonitrile , Src
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2005
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    796054