Author/Authors :
George P. Lahm، نويسنده , , Thomas P. Selby، نويسنده , , John H. Freudenberger، نويسنده , , Thomas M. Stevenson، نويسنده , , Brian J. Myers، نويسنده , , Gilles Seburyamo، نويسنده , , Ben K. Smith، نويسنده , , J. Lindsey Flexner، نويسنده , , Christopher E. Clark، نويسنده , , Daniel Cordova، نويسنده ,
Abstract :
A novel class of anthranilic diamides has been discovered with exceptional insecticidal activity on a range of Lepidoptera. These compounds have been found to exhibit their action by release of intracellular Ca2+ stores mediated by the ryanodine receptor. The discovery, synthesis, structure–activity, and biological results are presented.
Keywords :
Insecticide , Anthranilic , Diamide , Lepidoptera , Ryanodine , receptor