Author/Authors :
Young-Ger Suh، نويسنده , , Sun Nam Kim، نويسنده , , Dong-Yun Shin، نويسنده , , Soon-Sil Hyun، نويسنده , , Do-Sang Lee، نويسنده , , Kyung-Hoon Min، نويسنده , , Sae Mi Han، نويسنده , , Funan Li، نويسنده , , Eung-Chil Choi، نويسنده , , Seong-Hak Choi، نويسنده ,
Abstract :
For the systematic SAR study on mansonone F, a series of C6 and C9 analogs of mansonone F have been synthesized and their anti-MRSA activities were evaluated. Most of the analogs exhibited good or excellent anti-MRSA activities. In particular, the 6-n-butylmansonone F showed fourfold higher antibacterial activities compared to that of vancomycin.
Keywords :
Mansonone F , Anti-bacterial agent , MRSA , Sesquiterpenoid quinone
