Title of article
Photoreactive threading agent that specifically binds to abasic sites in DNA
Author/Authors
Alain Martelli، نويسنده , , Muriel Jourdan، نويسنده , , Jean-François Constant، نويسنده , , Martine Demeunynck، نويسنده , , Pascal Dumy، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
154
To page
157
Abstract
We report the synthesis and study of a photoreactive nitrobenzamide containing acridine that specifically interacts at abasic site in DNA by threading intercalation and introduces under irradiation a lesion on the opposite strand at the unpaired pyrimidine.
Keywords
DNA binders , DNA photodamaging , NMR , Abasic site , Acridine
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796334
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