Title of article
New potential antibacterials: A synthetic route to N-aryloxazolidinone/3-aryltetrahydroisoquinoline hybrids
Author/Authors
Rosa Griera، نويسنده , , Carme Cantos-Llopart، نويسنده , , Mercedes Amat، نويسنده , , Joan Bosch، نويسنده , , Juan-C. del Castillo، نويسنده , , Joan Huguet، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
3
From page
529
To page
531
Abstract
A synthetic route to a new structural type of potential antibacterials, with a hybrid 3-aryltetrahydroisoquinoline-6,7-diol/N-aryloxazolidinone structure, is reported. The synthesis involves the successive construction of the 3-aryltetrahydroisoquinoline and 4-substituted oxazolidinone moieties, the latter taking advantage of the functionalization at the para position of the aryl group.
Keywords
N-Aryloxazolidinones , 3-Aryltetrahydroisoquinolines , Linezolid , Antibacterials
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796409
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