Title of article
Synthesis and antiprotozoal activity of some new synthetic substituted quinoxalines
Author/Authors
Xu Hui، نويسنده , , Julie Desrivot، نويسنده , , Christian Bories، نويسنده , , Philippe M. Loiseau، نويسنده , , Xavier Franck، نويسنده , , Reynald Hocquemiller، نويسنده , , Bruno Figadere، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
6
From page
815
To page
820
Abstract
A series of 29 new quinoxalines was synthesized and evaluated in vitro against several parasites (Leishmania donovani, Trypanosoma brucei brucei, and Trichomonas vaginalis). Several of them displayed interesting activities, and particularly four quinoxaline amides showed in vitro antileishmanial properties (IC50 less than 20 μM).
Keywords
Quinoxalines , Amides , Amines , synthesis , bioassays
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796467
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