• Title of article

    Sarcosine based indandione hGlyT1 inhibitors

  • Author/Authors

    Christopher G. Thomson، نويسنده , , Karen Duncan، نويسنده , , Stephen R. Fletcher، نويسنده , , Ian T. Huscroft، نويسنده , , Gopalan Pillai، نويسنده , , Piotr Raubo، نويسنده , , Alison J. Smith، نويسنده , , Darren Stead، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2006
  • Pages
    4
  • From page
    1388
  • To page
    1391
  • Abstract
    A series of sarcosine based indandione hGlyT1 inhibitors has been developed. Optimization of substitution around the indandione and sarcosine moieties has led to highly potent inhibitors at hGlyT1, which show selectivity over a number of other receptors.
  • Keywords
    Sarcosine , Potent , Selectivity , GlyT1 inhibitors , Indandione
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2006
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    796584