Title of article :
Anti-HBV nucleotide prodrug analogs: Synthesis, bioreversibility, and cytotoxicity studies
Author/Authors :
Seetharamaiyer Padmanabhan، نويسنده , , John E. Coughlin، نويسنده , , Guangrong Zhang، نويسنده , , Cassandra J. Kirk، نويسنده , , Radhakrishnan P. Iyer، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
Several pronucleotide analogs of the model anti-HBV dinucleotide 3′-dA-U2′OMe have been synthesized and evaluated for stability, bioreversibility and cytotoxicity. These studies have helped identify potential candidates for further evaluation.
Keywords :
Anti-HBV nucleotide , prodrug , Bioreversibility , cytotoxicity , stability , Dinucleotide
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
