Title of article :
Synthesis and evaluation of an N-acylated photoactivatable analogue of glutathione as probe for glutathione-utilizing enzymes
Author/Authors :
Dan Bernardi، نويسنده , , Eric Battaglia، نويسنده , , Gilbert Kirsch، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
The first synthesis of an N-acylated photoactivatable analogue of reduced glutathione is described. N-(4-Benzoylbenzoyl)glutathione (8) was found to be an inhibitor and a photoaffinity probe of purified rat liver glutathione S-transferases.
Keywords :
Photoaffinity labelling , inhibition , Benzophenone , glutathione S-transferases , glutathione
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
