Title of article :
Indole-glucosides as novel sodium glucose co-transporter 2 (SGLT2) inhibitors. Part 2
Author/Authors :
Xiaoyan Zhang، نويسنده , , Maud Urbanski، نويسنده , , Mona Patel، نويسنده , , Geoffrey G. Cox، نويسنده , , Roxanne E. Zeck، نويسنده , , Haiyan Bian، نويسنده , , Bruce R. Conway، نويسنده , , Mary Pat Beavers، نويسنده , , Philip J. Rybczynski، نويسنده , , Keith T. Demarest، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Pages :
6
From page :
1696
To page :
1701
Abstract :
A series of indole-O-glucosides and C-glucosides was synthesized and evaluated in SGLT1 and SGLT2 cell-based functional assays. Compounds 2a and 2o were identified as potent SGLT2 inhibitors and screened in ZDF rats.
Keywords :
SGLT , glucosides
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2006
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
796647
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=796647
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