Title of article
Synthesis and antifungal activity of 6-hydroxycinnolines
Author/Authors
Chung-Kyu Ryu، نويسنده , , Jung Yoon Lee، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
1850
To page
1853
Abstract
6-Hydroxycinnolines 2 and cyclohexa-2,5-diene-1,4-dione derivatives 6 were synthesized and tested for in vitro antifungal activity against Candida and Aspergillus species. 6-Hydroxycinnolines 2 showed, in general, more potent antifungal activity against Candida species than the other cyclohexa-2,5-diene-1,4-diones. The results suggest that 6-hydroxycinnolines would be potent antifungal agents.
Keywords
6-Hydroxycinnoline , Antimicrobial compounds , antifungal , fungi , substitution effects
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796677
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