Title of article :
A novel ketone derivative of artemisinin biotransformed by Streptomyces griseus ATCC 13273
Author/Authors :
Jihua Liu، نويسنده , , You-Gen Chen، نويسنده , , Bo-Yang Yu، نويسنده , , Yijun Chen، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
A novel ketone derivative of artemisinin, artemisitone-9, was produced by the biotransformation of cultured Streptomyces griseus ATCC 13273. The structure of the ketone product was fully elucidated by various spectroscopic techniques, and the mechanism of generating such novel metabolite is also discussed.
Keywords :
regioselectivity , Artemisitone-9 , biotransformation , Streptomyces griseus ATCC 13273 , Artemisinin
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters