Title of article
Hydantoin derivatives as non-peptidic inhibitors of Ras farnesyl transferase
Author/Authors
Jinho Lee، نويسنده , , Jonghyun Kim، نويسنده , , Jong Sung Koh، نويسنده , , Hyun-Ho Chung، نويسنده , , Kyoung-Hee Kim، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
3
From page
1954
To page
1956
Abstract
1,3,5,5-Tetrasubstituted 2,4-imidazolinedione (hydantoin) derivatives were evaluated as Ftase inhibitors. Potent Ftase inhibitors without thiol or peptide were obtained in three steps.
Keywords
Hydantoin , 1 , 3 , 5-Tetrasubstituted 2 , 4-imidazolinedione , Farnesyl transferase , Non-peptidic , 5
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796700
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