Title of article
Discovery of novel hydroxy pyrazole based factor IXa inhibitor
Author/Authors
Dange Vijaykumar، نويسنده , , Paul A. Sprengeler، نويسنده , , Michael Shaghafi، نويسنده , , Jeffrey R. Spencer، نويسنده , , Brad A. Katz، نويسنده , , Christine Yu، نويسنده , , Roopa Rai، نويسنده , , Wendy B. Young، نويسنده , , Brian Schultz، نويسنده , , James Janc، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
2796
To page
2799
Abstract
Synthesis and biological data of a novel selective and efficacious factor IXa inhibitor are described along with its crystal structure in factor VIIa.
Keywords
Factor IXa inhibitors , Serine protease , Amidine , 3-Hydroxy pyrazole , Active site
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796872
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