Title of article :
Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4
Author/Authors :
Jay P. Powers and Nigel P.C. Walker، نويسنده , , Shyun Li، نويسنده , , Juan C. Jaen، نويسنده , , Jinqian Liu، نويسنده , , Nigel P.C. Walker، نويسنده , , Zhulun Wang، نويسنده , , Holger Wesche، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Pages :
4
From page :
2842
To page :
2845
Abstract :
High-throughput screening of a small-molecule compound library resulted in the identification of a novel series of N-acyl 2-aminobenzimidazoles that are potent inhibitors of interleukin-1 receptor-associated kinase-4.
Keywords :
IRAK-4 , kinase inhibitor , inflammation , kinase
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2006
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
796880
Link To Document :
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