Title of article
Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4
Author/Authors
Jay P. Powers and Nigel P.C. Walker، نويسنده , , Shyun Li، نويسنده , , Juan C. Jaen، نويسنده , , Jinqian Liu، نويسنده , , Nigel P.C. Walker، نويسنده , , Zhulun Wang، نويسنده , , Holger Wesche، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
2842
To page
2845
Abstract
High-throughput screening of a small-molecule compound library resulted in the identification of a novel series of N-acyl 2-aminobenzimidazoles that are potent inhibitors of interleukin-1 receptor-associated kinase-4.
Keywords
IRAK-4 , kinase inhibitor , inflammation , kinase
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796880
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