Title of article
Synthesis and preliminary antitumor activity evaluation of a DHA and doxorubicin conjugate
Author/Authors
Yuqiang Wang، نويسنده , , Lianfa Li، نويسنده , , Wei Jiang، نويسنده , , Zhaoqi Yang، نويسنده , , Zaijun Zhang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
2974
To page
2977
Abstract
A conjugate of DHA and doxorubicin (DHA–Dox) was synthesized, and its antitumor activity was evaluated in vitro against L1210 leukemia cells and in experimental animal tumor models including L1210 leukemia and B16 melanoma. DHA–Dox showed a greatly improved antitumor efficacy compared to free doxorubicin.
Keywords
doxorubicin , drug delivery , Anticancer , DHA
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796909
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