Title of article
Preparation and biochemical evaluation of fluorenone-containing lipid analogs
Author/Authors
Thomas A. Spencer، نويسنده , , Pingzhen Wang، نويسنده , , Janeta V. Popovici-Müller، نويسنده , , Ithan D. Peltan، نويسنده , , Phoebe E. Fielding، نويسنده , , Christopher J. Fielding، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
5
From page
3000
To page
3004
Abstract
Syntheses are described of fatty acid analogs 5 and 6, and cholesterol (2) analogs 7 and 8 containing fluorenone groups, which are both photoactivable and fluorescent. The potential of the analogs of 2 as biochemical research tools has been demonstrated by the findings that 7 and 8 can replace 2 in apolipoprotein A-I-induced cellular efflux of 2 and that fluorescence is easily visible at the surface of smooth muscle cells equilibrated with 8.
Keywords
lipids , cholesterol , fatty acids , Fluorenones
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
796915
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