Title of article :
Synthesis and photocytotoxic activity of new chlorin–polyamine conjugates
Author/Authors :
Guillaume Garcia، نويسنده , , Vincent Sol، نويسنده , , Jean-François Lamarche، نويسنده , , Robert Granet، نويسنده , , Michel Guilloton، نويسنده , , Yves Champavier، نويسنده , , Pierre Krausz، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
This paper reports the synthesis of new chlorin–polyamine conjugates designed to improve the targeting of cancer cells. Photocytotoxic activity of these photosensitizers was tested against human chronic myelogenous leukemia cells (K562) and compared to the effects of Photofrin II® and chlorin e6.
Keywords :
Chlorin e6 , Water-soluble chlorins , Polyamines , Photodynamic therapy
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
