Author/Authors :
Xuqing Zhang، نويسنده , , Xiaojie Li، نويسنده , , George F. Allan، نويسنده , , Amy Musto، نويسنده , , Scott G. Lundeen، نويسنده , , Zhihua Sui، نويسنده ,
Abstract :
A novel series of tetracyclic indoles have been designed, synthesized and evaluated as androgen receptor (AR) ligands. Studies of structure–activity relationships (SARs) were investigated, which led to some compounds in this series as strong binders to androgen receptors.