Title of article
Binding of methoxy-substituted N1-benzenesulfonylindole analogs at human 5-HT6 serotonin receptors
Author/Authors
Uma Siripurapu، نويسنده , , Renata Kolanos، نويسنده , , Malgorzata Dukat، نويسنده , , Bryan L. Roth، نويسنده , , Richard A. Glennon، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
3793
To page
3796
Abstract
Comparison of several amine-substituted and methoxy-substituted analogs of N1-(4-aminobenzene)sulfonylindole suggests that these substituents might contribute to the 5-HT6 serotonin receptor affinity of these agents via their electronic effect on the indolic nucleus. Their 1,2,3,4-tetrahydrocarbazole counterparts behave differently.
Keywords
serotonin receptors , Indole analogs , 5-HT6
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797080
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