Title of article
Synthesis of biotinylated photoaffinity probes based on arylsulfonamide γ-secretase inhibitors
Author/Authors
Haruhiko Fuwa، نويسنده , , Kenichi Hiromoto، نويسنده , , Yasuko Takahashi، نويسنده , , Satoshi Yokoshima، نويسنده , , Toshiyuki Kan، نويسنده , , Tohru Fukuyama، نويسنده , , Takeshi Iwatsubo، نويسنده , , Taisuke Tomita، نويسنده , , Hideaki Natsugari، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
6
From page
4184
To page
4189
Abstract
Synthesis and biological evaluation of an arylsulfonamide class of γ-secretase inhibitors are described. Design, synthesis, and biological evaluation of multifunctional molecular probes harboring a benzophenone photophore as a cross-linking group and a biotin tag are also reported.
Keywords
Photoaffinity probes , ?-Secretase inhibitors , structure–activity relationships , Arylsulfonamides
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797158
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