Title of article
N-(1,2-Diphenylethyl)piperazines: A new class of dual serotonin/noradrenaline reuptake inhibitor
Author/Authors
M. Jonathan Fray، نويسنده , , Gerwyn Bish، نويسنده , , Alan D. Brown، نويسنده , , Paul V. Fish، نويسنده , , Alan Stobie، نويسنده , , Florian Wakenhut، نويسنده , , Gavin A. Whitlock، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
4345
To page
4348
Abstract
The synthesis and structure–activity relationships of a novel series of piperazine derivatives as dual inhibitors of serotonin and noradrenaline reuptake is described. Two compounds possessed comparable in vitro profiles to the dual reuptake inhibitor duloxetine.
Keywords
Serotonin , noradrenaline , Reuptake inhibition , neurotransmitters , depression , incontinence
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797190
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