Title of article :
Antibacterial activity of pyrrolopyridine-substituted oxazolidinones: synthesis and in vitro SAR of various C-5 acetamide replacements
Author/Authors :
Steven D. Paget، نويسنده , , Christine M. Boggs، نويسنده , , Barbara D. Foleno، نويسنده , , Raul M. Goldschmidt، نويسنده , , Dennis J. Hlasta، نويسنده , , Michele A. Weidner-Wells، نويسنده , , Harvey M. Werblood، نويسنده , , Karen Bush and Osnat Herzberg، نويسنده , , Mark J. Macielag، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Pages :
6
From page :
4537
To page :
4542
Abstract :
A series of pyrrolopyridine-substituted oxazolidinones containing various C-5 acetamide isosteres was synthesized and the structure–antibacterial activity relationships determined against a representative panel of susceptible and resistant Gram-positive bacteria.
Keywords :
Pyrrolopyridine-substituted oxazolidinones , Vancomycin-resistant Enterococcus faecium , C-5 acetamide isosteres , Antibacterial agents , Methicillin-resistant Staphylococcus aureus
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2006
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
797225
Link To Document :
https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=797225
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