Title of article
Synthesis and pharmacological study of novel pyrido-quinazolone analogues as anti-fungal, antibacterial, and anticancer agents
Author/Authors
Anjani K. Tiwari، نويسنده , , A.K. Mishra، نويسنده , , Aruna Bajpai، نويسنده , , Pushpa Mishra، نويسنده , , R.K. Sharma، نويسنده , , V.K. Pandey، نويسنده , , Vinay Kumar Singh، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
5
From page
4581
To page
4585
Abstract
A versatile method for novel pyrido-quinazolones was described here and tested for anti-fungal, antibacterial, and anticancerous activities. These synthesized compounds were characterized on the basis of spectroscopic techniques and evaluated for specific radiopharmaceuticals. Preliminary radiolabeling results with 99mTc and biological evaluation studies showed promising results for further evaluation in vivo. The efficiency of labeling was more than 98% and complexes were stable for about 18 h at 25 °C in the presence of serum.
Keywords
Antibacterial , Anti-fungal , Pyrido-quinazolones , Radiolabeling , Radiopharmaceuticals
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797234
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