Title of article
Structure–activity relationships for the linker in a series of pyridinyl-alkynes that are antagonists of the metabotropic glutamate receptor 5 (mGluR5)
Author/Authors
Peter Bach، نويسنده , , Karolina Nilsson، نويسنده , , Tor Svensson، نويسنده , , Udo Bauer، نويسنده , , Lance G. Hammerland، نويسنده , , Alecia Peterson، نويسنده , , Andreas W?llberg، نويسنده , , Krister ?sterlund، نويسنده , , David Karis، نويسنده , , Maria Boije، نويسنده , , David Wensbo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
4788
To page
4791
Abstract
Studies of structure–activity relationships for the linker in a new series of metabotropic glutamate receptor 5 antagonists are presented together with in vitro and in vivo pharmacokinetic data.
Keywords
mGluR5 antagonists , Pyridinyl-alkynes , SAR , Gastro-esophageal reflux disease (GERD)
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797278
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