Title of article
Synthesis and antiproliferative activity of substituted benzopyranoisoindoles: A new class of cytotoxic compounds
Author/Authors
Christiana Hadjipavlou، نويسنده , , Ioannis K. Kostakis، نويسنده , , Nicole Pouli، نويسنده , , Panagiotis Marakos، نويسنده , , Harris Pratsinis، نويسنده , , Dimitris Kletsas، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
4822
To page
4825
Abstract
A series of novel aminosubstituted benzopyranoisoindoles possessing structural analogy to an active nitracrine metabolite are reported. The compounds exhibited interesting cytotoxic activity against a panel of cell lines, which was maximized by the presence of both 1-dialkylaminoethyl and 3-nitro substituents.
Keywords
2-c , d]isoindoles , antiproliferative activity , DNA-content analysis , 3
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797286
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