Title of article :
Enhanced reactivity of amino-modified oligonucleotides by insertion of aromatic residue
Author/Authors :
Naoshi Kojima، نويسنده , , Maiko Sugino، نويسنده , , Akiko Mikami، نويسنده , , Ken Nonaka، نويسنده , , Yumi Fujinawa، نويسنده , , Isamu Muto، نويسنده , , Kenichi Matsubara، نويسنده , , Eiko Ohtsuka-Tsurumi، نويسنده , , Yasuo Komatsu، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Pages :
4
From page :
5118
To page :
5121
Abstract :
We developed novel amino-modifying reagents, of which an amino group was connected with an aromatic residue by aliphatic linker. It was proved that the insertion of the aromatic residue could increase the reactivity of the amino group on oligonucleotides in comparison with conventional amino-modification.
Keywords :
Amino-modified oligonucleotide , Hydrophobic interaction , Aromatic group
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2006
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
797341
Link To Document :
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