Title of article
Enhanced reactivity of amino-modified oligonucleotides by insertion of aromatic residue
Author/Authors
Naoshi Kojima، نويسنده , , Maiko Sugino، نويسنده , , Akiko Mikami، نويسنده , , Ken Nonaka، نويسنده , , Yumi Fujinawa، نويسنده , , Isamu Muto، نويسنده , , Kenichi Matsubara، نويسنده , , Eiko Ohtsuka-Tsurumi، نويسنده , , Yasuo Komatsu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
5118
To page
5121
Abstract
We developed novel amino-modifying reagents, of which an amino group was connected with an aromatic residue by aliphatic linker. It was proved that the insertion of the aromatic residue could increase the reactivity of the amino group on oligonucleotides in comparison with conventional amino-modification.
Keywords
Amino-modified oligonucleotide , Hydrophobic interaction , Aromatic group
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2006
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
797341
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