Title of article :
Derivatives of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acids as novel fibrinogen receptor antagonists
Author/Authors :
Olga L. Malovichko، نويسنده , , Anna S. Petrus، نويسنده , , Andrei A. Krysko، نويسنده , , Tatyana A. Kabanova، نويسنده , , Sergei A. Andronati، نويسنده , , Tamara L. Karaseva، نويسنده , , Anna V. Kiriyak، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
The novel fibrinogen receptor antagonists containing fragments of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acids were synthesized and successfully tested for their ability to inhibit platelet aggregation in vitro and to block FITC-Fg binding to αIIbβ3 on washed human platelets.
Keywords :
2 , platelet aggregation , 3 , 4-Tetrahydroisoquinoline , Fibrinogen receptor antagonists , ?IIb?3 , 1 , RGD mimetics
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
